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Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo

Muto, S

Headaches and Dizziness: These effects can occur, particularly during the initial phase of therapy

Because comprehensive controlled human safety data are not established, any conclusions about tolerability in people remain unconfirmed

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years