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IGF-1 LR3 is engineered with an N-terminal extension and Arg3 substitution that reduces IGFBP-3 binding, extending its effective activity substantially longer in preclinical models

Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles

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Lysates were then centrifuged at 12,000 rpm for 30 min at 4 C, and the cleared supernatants were filtered through 0.45 m spin filters (Millipore) to remove cell debris

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Exploiting ferroptosis vulnerabilities in cancer