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Finally, the mold was transferred to an oven (45 C) and placed for 72 h to for demolding, The pure microneedles (MN), Qu loaded microneedles (Qu/MN) and ZC-MSN loaded microneedles (ZC/MN) were also prepared as control groups follow the same protocol using the corresponding ingredients with the same amounts

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Heffernan 2001b This metabolic selectivity has a dosage implication: once the beta-3 receptors in adipose tissue are adequately occupied, additional peptide does not proportionally increase the lipolytic signal