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In order to display the implications of GST for individual patients, a generalized additive model (GAM) (with spline) incorporating the subject-specific (longitudinal) random effects was plotted and adjusted for other clinical parameters to predict the outcomes 28,29

3 vials: 9 mL 1 10 mL bottle 5 vials: 15 mL 2 10 mL bottles 6 vials: 18 mL 2 10 mL bottles Alcohol Swabs: One for the vial stopper + one for the injection site each day

Statements Author contributions AC and XC wrote and edited the article

Antioxid Redox Signal 2018;29:1727-45

Zeng H, Li J, Hou K, Wu Y, Chen H, Ning Z

Administration Intramuscular or Subcutaneous injection