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The aging of the global population anticipated the current marked increase in people with Alzheimer's disease (AD)

By midlife, NAD+ can drop by 50%, exacerbated by inflammation and lifestyle.[14] Factors like poor diet, sedentary behavior, or chronic stress further deplete NAD+ by activating consuming enzymes, creating a vicious cycle

Personally, alcohol led me to B12 deficiency in the first place

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