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Hyperoside (0.10.5% in HPL) directly inhibits adriamycin-induced mitochondrial dysfunction and podocyte injury through the inhibition of chondriokinesis in vivo and in vitro , thereby ameliorating renal and podocyte injury to reduce albuminuria in individuals with early diabetic nephropathy (Zhang et al., 2013

PMID: 21548867

Ascorbyl glucoside is a milder product, in that it doesnt have as much power in neutralizing free radicals

Research from 2016-2025 supports its role in: You'll usually find this in concentrations between 0.2-5%

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Metformin Metformin is an insulin-sensitizing drug used in the management of type 2 diabetes (Al-Kuraishy et al