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Conclusion and future perspectives Conclusions Mitochondrial dysfunction emerges as a pivotal unifying mechanism intricately linking CVDs and cognitive impairment
Ideally incorporate rigorous baseline and follow-up assessments: DEXA, body composition, visceral fat, renal function, endocrine panels, inflammatory biomarkers (IL-6, TNF-, SASP markers if available)
CIBERSORT analysis linked LPCAT3 expression to distinct immune cell infiltration profiles, suggesting an immune-metabolic regulatory role (78)
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Pickart and colleagues proposed that GHK functions as an "emergency response" molecule liberated by tissue injury