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Lautenschger et al., 2020

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Prenatal caffeine exposure induces liver developmental dysfunction in offspring rats

9 This calcification process is frequently found in the muscular arteries of the extremities in elderly people with diabetes mellitus and chronic kidney failure, 10 without remarkable narrowing of the arterial lumen

Published Phase 2 clinical trial data used doses of 1mg, 4mg, 8mg, and 12mg administered weekly via subcutaneous injection

In vitro , myricetin treatment of SH-SY5Y neuroblastoma cells exposed to 1-methyl-4-phenylpyridine (MPP + ) significantly reduces Fe 2+ and ROS levels, activates the NRF2/GPX4 signaling pathway, suppresses neuronal ferroptosis, and mitigates cellular injury (Gu et al., 2024)