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GLP-1 receptor agonists semaglutide and liraglutide have demonstrated menstrual cycle normalization in multiple RCTs, primarily through insulin sensitization

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GLP-1 and PMOS: The Strongest Case in 2026 GLP-1 receptor agonists including semaglutide (Ozempic/Wegovy) and liraglutide (Victoza/Saxenda) are the most evidence-supported peptide option for women with PMOS as of 2026

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