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Popular brands and key players (Euromonitor data): This market is dominated by Big Tobacco companies, which control around 88% of the market, with Philip Morris Internationals IQOS making up over 68% alone

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A dense network of capillaries lies just below the skin and facilitates gas exchange between the external environment and the circulatory system

While lung cancer is the biggest threat, smoking is also linked to cancer of the mouth, throat, bladder, kidney, larynx, and stomach, as well as cervical and pancreatic cancer

Within the brain, densities of these receptors are extremely high in the hippocampus and are also very high in the amygdala (both areas are heavily associated with stimulus, reward, addiction and so on)