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However, p53 seems to retard ferroptosis in certain cellular metabolic environments

Research has demonstrated that bortezomib-resistant cells in multiple myeloma redirect glucose toward the pentose phosphate pathway and serine synthesis pathway, enhancing their antioxidant capabilities

Phosphoglycerate dehydrogenase is encoded by the PHGDH gene which is located on chromosome 1p12 and is composed of 18 exons that generate a protein of 533 amino acids

These side effects often result from increased cell growth, tissue expansion, and shifts in metabolic processes, which are more pronounced with higher doses or prolonged use

Profiling at mRNA, protein, and metabolite levels reveals alterations in renal amino acid handling and glutathione metabolism in kidney tissue of pept2 / mice

Importantly, our target prediction approach did not incorporate data from RSV-infected cells, thus further supporting the notion that the predicted targets also work beyond the three viruses initially included in our analysis