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Pyroptosis was initially discovered in immune cells, but subsequent studies have shown that other cell types, including epithelial and endothelial cells, can also undergo pyroptosis

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Comparative studies of single-peptide versus multi-peptide activity on fibroblast migration, proliferation, and ECM organization

"Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey"

Tak YJ, Lee SY, Cho AR, Kim YS

By disrupting this interaction, the peptide releases p53 to trigger apoptosis selectively in senescent cells while sparing healthy cells (Baar et al., 2017)