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Therefore additional studies are needed to determine safety, feasibility, and efficacy

OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy

All mice were maintained under specific pathogen-free conditions under license and approval of local animal research ethics committee committee (Health Products Regulatory Authority [HPRA], Ireland) and European Union regulations

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Pharmacokinetics: blood-brain barrier and plasma stability A small set of pharmacokinetic studies in the early 1980s addressed two questions relevant to interpreting peripherally administered DSIP: does it cross the blood-brain barrier, and what is its plasma stability

PMCID: PMC11890406