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639 As shown in Figure 12, 38% of Alzheimer's and other dementia caregivers indicate that the physical stress of caregiving is high to very high.A10 Dementia caregivers are 1.5 times more likely to indicate substantial physical difficulty providing assistance to their care recipients compared with nondementia caregivers

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Another study showed that intra-articular injection of Botulinum Toxin A inhibited cartilage degradation in an OA model rat, and Lip-1 could further enhance this chondroprotective effect (Zeng et al., 2024)

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