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Domestic studies usually use cell and molecular biology experimental methods to explore the effects of metformin on the glioma cell cycle and apoptosis, and the research results show that metformin can significantly change the cycle distribution of glioma cells ( Mitochondria-dependent apoptosis pathway: metformin can induce the loss of mitochondrial membrane potential and release apoptosis-related factors such as cytochrome C, thereby activating the caspase cascade and ultimately leading to apoptosis (65)

Long-term plasticity at excitatory synapses on aspinous interneurons in area CA1 lacks synaptic specificity

Ru J, Li P, Wang J, Zhou W, Li B, Huang C, et al

Acetylcysteine may also be given through a percutaneous intratracheal catheter

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