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First added to tobacco in the 1920s, menthol reduces the harshness of cigarette smoke and the irritation from nicotine, which is part of the reason why menthol cigarettes may be more addictive

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Still a hypothesis While high numbers of goblet and club cells, laden with ACE2 receptors, may explain why smokers fall severely ill of COVID-19, the exact relationship between ACE2 and disease prognosis "remains to be demonstrated," Sheltzer and Smith noted