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May Influence Pain and Stress Response Pathways Some studies suggest DSIP may interact with pathways involved in pain perception and stress response, making it relevant in neurobiological research focused on central nervous system adaptability and resilience

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"Prenatal risk factors for autism: comprehensive meta-analysis"

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[114] (See Endogenous opiate precursor theory) After a preliminary 1998 study of three children with autism treated with secretin infusion reported improved GI function and dramatic improvement in behavior, many parents sought secretin treatment and a black market for the hormone developed quickly

Figure 5 Secondly, an in vitro pull-down experiment was performed with recombinant His-tagged TRX-f1, TRX-m1 and NTRC as bait proteins, in order to trap potential target proteins in the chloroplast extracts